ATP13A2 Human Gene Knockout Kit (CRISPR)

CAT#: KN215270LP

ATP13A2 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: ATP13A2
• Locus ID: 23400
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001141973, NM_001141974, NM_022089
• Synonyms: CLN12; HSA9947; KRPPD; PARK9
• Summary: This gene encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other substrates. Mutations in this gene are associated with Kufor-Rakeb syndrome (KRS), also referred to as Parkinson disease 9. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]