TAP2 Human Gene Knockout Kit (CRISPR)
CAT#: KN222611
TAP2 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | TAP2 |
Locus ID | 6891 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000544, NM_001290043, NM_018833 |
Synonyms | ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11 |
Summary | 'The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN222611BN | TAP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN222611LP | TAP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN222611RB | TAP2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN422611 | TAP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA104749 | TAP2 CRISPRa kit - CRISPR gene activation of human transporter 2, ATP binding cassette subfamily B member |
USD 1,290.00 |
{0} Product Review(s)
Be the first one to submit a review