BRCC45 (BRE) Human Gene Knockout Kit (CRISPR)
CAT#: KN401509
BRE - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN401509 is the updated version of KN201509.
USD 1,290.00
2 Weeks*
Size
Other products for "BABAM2"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | BABAM2 |
Locus ID | 9577 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001261840, NM_001329112, NM_001329113, NM_001329114, NM_001329115, NM_004899, NM_199191, NM_199192, NM_199193, NM_199194, NR_137437, NR_137438, NR_137439, NR_137440 |
Synonyms | BRCC4; BRCC45 |
Summary | This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA106412 | BABAM2 CRISPRa kit - CRISPR gene activation of human BRISC and BRCA1 A complex member 2 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.