PAH Human Gene Knockout Kit (CRISPR)
CAT#: KN404694
PAH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | PAH |
Locus ID | 5053 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000277, NM_001354304 |
Synonyms | PH; PKU; PKU1 |
Summary | 'This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN204694 | PAH - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN204694BN | PAH - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN204694LP | PAH - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN204694RB | PAH - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
GA103375 | PAH CRISPRa kit - CRISPR gene activation of human phenylalanine hydroxylase |
USD 1,290.00 |
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