RHOBTB1 Human Gene Knockout Kit (CRISPR)

CAT#: KN406310

RHOBTB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: RHOBTB1
• Locus ID: 9886
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001032380, NM_001242359, NM_014836, NM_198225, NR_024554, NR_024555, NR_024556, NM_001350902, NM_001350903, NM_001350904, NM_001350905, NM_001350906, NM_001350907, NM_001350908, NM_001350909, NM_001350910, NM_001350911
• Synonyms: 1700008H16Rik; 3110048G13Rik; AI173445; AI573858; AV350930; KIAA0740, MGC33059, MGC33841; MGC107538; Rho-related BTB domain containing 1
• Summary: The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]