BCKDHB Human Gene Knockout Kit (CRISPR)
CAT#: KN408059
BCKDHB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN408059 is the updated version of KN208059.
USD 1,290.00
2 Weeks*
Size
Other products for "BCKDHB"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | BCKDHB |
Locus ID | 594 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000056, NM_001318975, NM_183050, NR_134945 |
Synonyms | BCKDE1B; BCKDH E1-beta; E1B |
Summary | 'This gene encodes the E1 beta subunit of branched-chain keto acid dehydrogenase, which is a multienzyme complex associated with the inner membrane of mitochondria. This enzyme complex functions in the catabolism of branched-chain amino acids. Mutations in this gene have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation and feeding problems. Alternative splicing at this locus results in multiple transcript variants. [provided by RefSeq, Jan 2016]' |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA100408 | BCKDHB CRISPRa kit - CRISPR gene activation of human branched chain keto acid dehydrogenase E1 subunit beta |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.