SorLA (SORL1) Human Gene Knockout Kit (CRISPR)
CAT#: KN414154
SORL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN414154 is the updated version of KN214154.
USD 1,290.00
2 Weeks*
Size
Other products for "SorLA"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | SorLA |
Locus ID | 6653 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_003105 |
Synonyms | C11orf32; gp250; LR11; LRP9; SORLA; SorLA-1 |
Summary | 'This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease. [provided by RefSeq, Feb 2016]' |
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FAQs |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA104563 | SORL1 CRISPRa kit - CRISPR gene activation of human sortilin related receptor 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.