ASPM Human Gene Knockout Kit (CRISPR)
CAT#: KN414770
ASPM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | ASPM |
Locus ID | 259266 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001206846, NM_018136 |
Synonyms | ASP; Calmbp1; MCPH5 |
Summary | This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
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KN214770 | ASPM - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN214770BN | ASPM - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN214770LP | ASPM - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN214770RB | ASPM - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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GA116913 | ASPM CRISPRa kit - CRISPR gene activation of human abnormal spindle microtubule assembly |
USD 1,290.00 |
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