KCNG4 Human Gene Knockout Kit (CRISPR)

CAT#: KN416146

KCNG4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: KCNG4
• Locus ID: 93107
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_133490, NM_172347
• Synonyms: KV6.3; KV6.3, KV6.4, MGC4558, MGC129609; KV6.4; MGC4558; MGC129609; potassium voltage-gated channel, subfamily G, member 4; potassium voltage-gated channel, subfamily G, member 4, isoform 1; voltage-gated potassium channel Kv6.3
• Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]