FGF14 Human Gene Knockout Kit (CRISPR)

CAT#: KN419002

FGF14 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: FGF14
• Locus ID: 2259
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_004115, NM_175929, NM_001321931, NM_001321932, NM_001321933, NM_001321934, NM_001321935, NM_001321936, NM_001321937, NM_001321938, NM_001321939, NM_001321940, NM_001321941, NM_001321942, NM_001321943, NM_001321944, NM_001321945, NM_001321946, NM_001321947, NM_001321948, NM_001321949
• Synonyms: FGF-14; FHF-4; FHF4; SCA27
• Summary: 'The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]'