Girdin (CCDC88A) Human Gene Knockout Kit (CRISPR)
CAT#: KN423752
CCDC88A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN423752 is the updated version of KN223752.
USD 1,290.00
2 Weeks*
Size
Other products for "CCDC88A"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | CCDC88A |
Locus ID | 55704 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001135597, NM_001254943, NM_018084, NM_001365480 |
Synonyms | APE; GIRDIN; GIV; GRDN; HkRP1; KIAA1212; PEHO |
Summary | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA110898 | CCDC88A CRISPRa kit - CRISPR gene activation of human coiled-coil domain containing 88A |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.