Capzb Mouse Gene Knockout Kit (CRISPR)
CAT#: KN502524
Capzb - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN502524 is the updated version of KN302524.
USD 1,290.00
2 Weeks*
Size
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Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Capzb |
Locus ID | 12345 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001037761, NM_001271405, NM_001271406, NM_009798 |
Synonyms | 1700120C01Rik; AI325129; Cappb1; CPB1; CPB2; CPbeat2; CPbeta1; CPbeta2 |
Summary | This gene encodes the beta subunit of a highly conserved filamentous actin capping protein that binds the barbed end of filamentous actin to stabilize it and terminate elongation. Interaction of this protein with the barbed end of the actin filament occurs through binding of the amphipathic helix at the C-terminus to the hydrophobic cleft on the actin molecule. This gene is required for a variety of dynamic actin-mediated processes including organization of lamellipodia and filopodia, growth cone morphology and neurite outgrowth in hippocampal neurons, and asymmetric spindle migration and polar body extrusion during oocyte maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA200522 | Capzb CRISPRa kit - CRISPR gene activation of mouse capping protein (actin filament) muscle Z-line, beta |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.