Inpp5b Mouse Gene Knockout Kit (CRISPR)

CAT#: KN508347

Inpp5b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN508347 is the updated version of KN308347.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol Inpp5b
Locus ID 16330
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_008385, NR_126474
Synonyms 5PTase; AW260155; INPP5P
Summary This gene encodes a member of the inositol polyphosphate-5-phosphatase (INPP5) family. This protein hydrolyzes the 5' phosphate from phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol-1,4,5-trisphosphate, which results in changes to multiple signaling pathways. This protein may be involved in protein trafficking and secretion. Homozygous knockout mice exhibit impaired spermatogenesis and male sterility. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Other Versions

SKU Description Size Price
GA202171 Inpp5b CRISPRa kit - CRISPR gene activation of mouse inositol polyphosphate-5-phosphatase B
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.