Senp7 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN515518

Senp7 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: Senp7
• Locus ID: 66315
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001003971, NM_001003972, NM_001003973, NM_001304503, NM_025483, NM_001360073
• Synonyms: 2410152H17Rik; 2810413I22Rik; 2900036C23Rik; 6030449K19Rik; AI790676; mKIAA1707
• Summary: This gene encodes a SUMO deconjugating enzyme of the Sentrin/SUMO-specific protease (SENP) family. The encoded protein is a protease that exhibits deSUMOylating activity towards proteins involved in chromatin remodeling and promotes chromatin relaxation for DNA repair or transcription. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015]