DPM2 (NM_003863) Human Mass Spec Standard
CAT#: PH303919
DPM2 MS Standard C13 and N15-labeled recombinant protein (NP_003854)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC203919 |
Predicted MW | 9.3 kDa |
Protein Sequence |
>RC203919 protein sequence
Red=Cloning site Green=Tags(s) MATGTDQVVGLGLVAVSLIIFTYYTAWVILLPFIDSQHVIHKYFLPRAYAVAIPLAAGLLLLLFVGLFIS YVMLKSKRVTKKAQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_003854 |
RefSeq Size | 1561 |
RefSeq ORF | 252 |
Synonyms | CDG1U |
Locus ID | 8818 |
UniProt ID | O94777 |
Cytogenetics | 9q34.11 |
Summary | Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq, Jul 2008] |
Protein Families | Transmembrane |
Protein Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways, N-Glycan biosynthesis |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418387 | DPM2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY418387 | Transient overexpression lysate of dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2) |
USD 396.00 |
|
TP303919 | Recombinant protein of human dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2) |
USD 823.00 |
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