GI24 (C10orf54) (NM_022153) Human Mass Spec Standard

CAT#: PH304547

C10orf54 MS Standard C13 and N15-labeled recombinant protein (NP_071436)

Product Images

Coomassie blue staining of purified VSIR protein (Cat# TP304547). The protein was produced from HEK293T cells transfected with VSIR cDNA clone (Cat# RC204547) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC204547
• Predicted MW: 33.9 kDa
• Protein Sequence:
  Sequence Link

  >RC204547 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MGVPTALEAGSWRWGSLLFALFLAASLGPVAAFKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYK
  TWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHDLAQRHGLESASDHHGNFSITMRNLTLLD
  SGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYPSSSQESENITAAALATGACIVGILCLPL
  ILLLVYKQRQAASNRRAQELVRMDSNIQGIENPGFEASPPAQGIPEAKVRHPLSYVAQRQPSESGRHLLS
  EPSTPLSPPGPGDVFFPSLDPVPDSPNFEVI
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_071436
• RefSeq Size: 4774
• RefSeq ORF: 933
• Synonyms: B7-H5; B7H5; C10orf54; DD1alpha; Dies1; GI24; PD-1H; PP2135; SISP1; VISTA
• Locus ID: 64115
• UniProt ID: Q9H7M9
• Cytogenetics: 10q22.1
• Summary: Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777). [UniProtKB/Swiss-Prot Function]
• Protein Families: Transmembrane