TNFSF18 (NM_005092) Human Mass Spec Standard

CAT#: PH310901

TNFSF18 MS Standard C13 and N15-labeled recombinant protein (NP_005083)

Product Images

Coomassie blue staining of purified TNFSF18 protein (Cat# TP310901). The protein was produced from HEK293T cells transfected with TNFSF18 cDNA clone (Cat# RC210901) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC210901
• Predicted MW: 20.31 kDa
• Protein Sequence:
  Sequence Link

  >RC210901 representing NM_005092
  Red=Cloning site Green=Tags(s)
  
  MCLSHLENMPLSHSRTQGAQRSSWKLWLFCSIVMLLFLCSFSWLIFIFLQLETAKEPCMAKFGPLPSKWQ
  MASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTY
  ELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFIS
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_005083
• RefSeq Size: 748
• RefSeq ORF: 531
• Synonyms: AITRL; GITRL; hGITRL; TL6; TNLG2A
• Locus ID: 8995
• UniProt ID: Q9UNG2, A0A0U5JXL4
• Cytogenetics: 1q25.1
• Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction