SH3BP2 (NM_001122681) Human Mass Spec Standard

CAT#: PH325960

SH3BP2 MS Standard C13 and N15-labeled recombinant protein (NP_001116153)

  View other "SH3BP2" proteins (7)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225960
Predicted MW 62.2 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001116153
RefSeq Size 9068
RefSeq ORF 1683
Synonyms 3BP-2; 3BP2; CRBM; CRPM; RES4-23
Locus ID 6452
UniProt ID P78314, A0A384N6E5
Cytogenetics 4p16.3
Summary 'The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]'
Protein Families Druggable Genome
Protein Pathways Natural killer cell mediated cytotoxicity

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