AHA1 / AHSA1 (19-337) Human Protein

CAT#: AR09004PU-S

AHA1 / AHSA1 (19-337) human recombinant protein, 0.1 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MATNVNNWHW TERDASNWST DKLKTLFLAV QVQNEEGKCE VTEVSKLDGE ASINNRKGKL IFFYEWSVKL NWTGTSKSGV QYKGHVEIPN LSDENSVDEV EISVSLAKDE PDTNLVALMK EEGVKLLREA MGIYISTLKT EFTQGMILPT MNGESVDPVG QPALKTEERK AKPAPSKTQA RPVGVKIPTC KITLKETFLT SPEELYRVFT TQELVQAFTH APATLEADRG GKFHMVDGNV SGEFTDLVPE KHIVMKWRFK SWPEGHFATI TLTFIDKNGE TELCMEGRGI PAPEEERTRQ GWQRYYFEGI KQTFGYGARL
• Predicted MW: 36.1 kDa
• Concentration: lot specific
• Purity: >95% > / = 95% by SDS PAGE
• Buffer: Presentation State: Purified
  State: Liquid
  Buffer System: 20 mM Tris pH 8.0 , 2 mM EDTA
• Preparation: Liquid
• Protein Description: Recombinant Aha1 was expressed in E. coli and purified by using conventional chromatography techniques.
• Storage: Store at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001308370
• Locus ID: 10598
• UniProt ID: O95433, G3V438
• Cytogenetics: 14q24.3
• Synonyms: AHA1; C14orf3; hAha1; p38
• Summary: Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). [UniProtKB/Swiss-Prot Function]