RAIDD (1-199, His-tag) Human Protein

CAT#: AR09013PU-N

RAIDD (1-199, His-tag) human recombinant protein, 0.1 mg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLMLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE
• Tag: His-tag
• Predicted MW: 24.9 kDa
• Concentration: lot specific
• Purity: >95% >/= 95% by SDS PAGE
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: 20 mM TRIS pH 8.0, 20 % glycerol
• Preparation: Liquid purified protein
• Protein Description: Recombinant CRADD protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
• Note: NCBI Accession No.: NP_003796
• Storage: Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_001307028
• Locus ID: 8738
• UniProt ID: P78560, Q53XL1, Q8IY43
• Cytogenetics: 12q22
• Synonyms: MRT34; RAIDD
• Summary: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
• Protein Families: Druggable Genome