BCAS2 / DAM1 (1-225, His-tag) Human Protein

CAT#: AR09854PU-S

BCAS2 / DAM1 (1-225, His-tag) human recombinant protein, 10 µg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAGT GLVAGEVVVD ALPYFDQGYE APGVREAAAA LVEEETRRYR PTKNYLSYLT APDYSAFETD IMRNEFERLA ARQPIELLSM KRYELPAPSS GQKNDITAWQ ECVNNSMAQL EHQAVRIENL ELMSQHGCNA WKVYNENLVH MIEHAQKELQ KLRKHIQDLN WQRKNMQLTA GSKLREMESN WVSLVSKNYE IERTIVQLEN EIYQIKQQHG EANKENIRQD F
• Tag: His-tag
• Predicted MW: 30.3 kDa
• Concentration: lot specific
• Purity: >85%
• Buffer: Presentation State: Purified
  State: Liquid purified protein
  Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 5mM DTT, 0.2M NaCl
• Preparation: Liquid purified protein
• Protein Description: Recombinant human BCAS2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_005863
• Locus ID: 10286
• UniProt ID: O75934, B2R7W3
• Cytogenetics: 1p13.2
• Synonyms: DAM1; Snt309; SPF27
• Summary: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). [UniProtKB/Swiss-Prot Function]
• Protein Pathways: Spliceosome