Azurocidin Human Protein
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Other products for "AZU1"
Specifications
Product Data | |
Species | Human |
Expression Host | Neutrophils |
Concentration | lot specific |
Purity | > 95 % by SDS-PAGE |
Buffer | 20mM HEPES-NaOH, pH 8.0 containing 0.4M Sodium Chloride, 0.1mM PMSF, 0.02% Lubrol. Preservative: Proprietary formula containing 0.1% preservative, bromo-nitro-dioxane/methylisothiazolone |
Preparation | Liquid purified protein |
Storage | Store the antigen at -20°C. Avoid multiple freeze/thaw cycles. Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001691 |
Locus ID | 566 |
Cytogenetics | 19p13.3 |
Synonyms | AZAMP; AZU; CAP37; HBP; hHBP; HUMAZUR; NAZC |
Summary | 'Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]' |
Protein Families | Druggable Genome, Protease |
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