CD54 / ICAM1 Human Protein

CAT#: AR31170PU-N

CD54 / ICAM1 human recombinant protein, 50 µg

Specifications

Product Data

• Species: Human
• Expression Host: CHO
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  QTSVSPSKVI LPRGGSVLVT CSTSCDQPKL LGIETPLPKK ELLLPG NNRK VYELSNVQED SQPMCYSNCP DGQSTAKTFL TVYWTPERVE L APLPSWQPV GKNLTLRCQV EGGAPRANLT VVLLRGEKEL KREPAVG EPA EVTTTVLVRR DHHGANFSCR TELDLRPQGL ELFENTSAPY QL QTFVLPAT PPQLVSPRVL EVDTQGTVVC SLDGLFPVSE AQVHLALG DQ RLNPTVTYGN DSFSAKASVS VTAEDEGTQR LTCAVILGNQ SQE TLQTVTI YSFPAPNVIL TKPEVSEGTE VTVKCEAHPR AKVTLNGVP A QPLGPRAQLL LKATPEDNGR SFSCSATLEV AGQLIHKNQT RELR VLYGPR LDERDCPGNW TWPENSQQTP MCQAWGNPLP ELKCLKDGTF PLPIGESVTV TRDLEGTYLC RARSTQGEVT RKVTVNVLSP RYE
• Predicted MW: 72-80 kDa
• Purity: >98% by SDS-PAGE and HPLC
• Buffer: Presentation State: Purified
  State: Lyophilized purified protein
  Stabilizer: None
• Bioactivity: Biological: ICAM-1 supported the adhesion of more than 50% PMA-stimulated HSB2 cells to plates coated at 25μg/ml ICAM-1 concentration
• Endotoxin: < 0.1 ng per µg of ICAM-1
• Preparation: Lyophilized purified protein
• Protein Description: Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1. Monomeric glycosylated ICAM-1 migrates at an apparent molecular weight of approximately 72.0-80.0 kDa by SDS-PAGE analysis under reducing conditions.
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_000192
• Locus ID: 3383
• UniProt ID: P05362, A0A384MEK5
• Cytogenetics: 19p13.2
• Synonyms: BB2; CD54; P3.58
• Summary: 'This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Viral myocarditis