CKBB Human Protein

CAT#: BIN015

CKBB human recombinant protein, 1 mg

Specifications

Product Data

• Species: Human
• Expression Host: Pichia pastoris
• Concentration: lot specific
• Purity: >95% pure by SDS-PAGE. Purified under non-denaturing conditions.
• Buffer: Presentation State: Azide Free
  State: Liquid purified protein
  Buffer System: 10mM Bis-Tris-HCl, 0.5mM DTT, 0.5mM EDTA, 50% Glycerol, pH 6.0 +/- 0.2 containing no preservatives
• Preparation: Liquid purified protein
• Applications: Suitable for use in ELISA.
• Protein Description: Recombinant Creatine Kinase BB (CK-BB) Isoenzyme. Full length Creatine Kinase BB isoenzyme with amino acid sequence identical to the native enzyme. CKBB is a 47 kDa dimeric protein comprised of 2 identical B subunits. Purified in the enzymatically active form. Reacts with polyclonal antibodies to BB isoenzyme in ELISA.
• Storage: Store at -20° to -70°C.
  Aliquot to avoid multiple freeze/thaw cycles.
• Stability: Shelf life: six months from despatch.

Reference Data

• RefSeq: NP_001814
• Locus ID: 1152
• UniProt ID: P12277, V9HWH2
• Cytogenetics: 14q32.33
• Synonyms: B-CK; BCK; CKBB; CPK-B; HEL-211; HEL-S-29
• Summary: 'The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways