GRAF (ARHGAP26) (NM_015071) Human Recombinant Protein

CAT#: TP313996

Recombinant protein of human Rho GTPase activating protein 26 (ARHGAP26), transcript variant 1

Product Images

Coomassie blue staining of purified ARHGAP26 protein (Cat# TP313996). The protein was produced from HEK293T cells transfected with ARHGAP26 cDNA clone (Cat# RC213996) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC213996. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 92.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_055886
• Locus ID: 23092
• UniProt ID: Q9UNA1
• Cytogenetics: 5q31.3
• Refseq Size: 6518
• Refseq ORF: 2442
• Synonyms: GRAF; GRAF1; OPHN1L; OPHN1L1
• Summary: Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
• Protein Families: Druggable Genome