MYBPC3 (NM_000256) Human Recombinant Protein
CAT#: TP317720
Purified recombinant protein of Homo sapiens myosin binding protein C, cardiac (MYBPC3)
View other "MYBPC3" proteins (3)
Special Offer: Get a 20% discount on this product. Use code: "MVPro20".
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC217720. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 140.6 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000247 |
Locus ID | 4607 |
UniProt ID | Q14896, A5YM48 |
Cytogenetics | 11p11.2 |
Refseq Size | 4200 |
Refseq ORF | 3822 |
Synonyms | CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C |
Summary | 'MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]' |
Protein Families | Druggable Genome |
Protein Pathways | Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424835 | MYBPC3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LY424835 | Transient overexpression lysate of myosin binding protein C, cardiac (MYBPC3) |
USD 605.00 |
|
PH317720 | MYBPC3 MS Standard C13 and N15-labeled recombinant protein (NP_000247) |
USD 2,055.00 |
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