VAV3 (NM_001079874) Human Recombinant Protein
CAT#: TP318352
Recombinant protein of human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2
View other "VAV3" proteins (7)
Special Offer: Get a 20% discount on this product. Use code: "MVPro20".
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC218352. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 32.4 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001073343 |
Locus ID | 10451 |
UniProt ID | Q9UKW4 |
Cytogenetics | 1p13.3 |
Refseq Size | 3115 |
Refseq ORF | 861 |
Synonyms | FLJ40431 |
Summary | This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | B cell receptor signaling pathway, Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, T cell receptor signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC416860 | VAV3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC421571 | VAV3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY416860 | Transient overexpression lysate of vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 1 |
USD 605.00 |
|
LY421571 | Transient overexpression lysate of vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2 |
USD 396.00 |
|
PH318352 | VAV3 MS Standard C13 and N15-labeled recombinant protein (NP_001073343) |
USD 2,055.00 |
|
PH320550 | VAV3 MS Standard C13 and N15-labeled recombinant protein (NP_006104) |
USD 2,055.00 |
|
TP320550 | Recombinant protein of human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 1 |
USD 748.00 |
{0} Product Review(s)
Be the first one to submit a review