DOCK8 (NM_203447) Human Recombinant Protein

CAT#: TP322789

Recombinant protein of human dedicator of cytokinesis 8 (DOCK8)

Product Images

Coomassie blue staining of purified DOCK8 protein (Cat# TP322789). The protein was produced from HEK293T cells transfected with DOCK8 cDNA clone (Cat# RC222789) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC222789. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 238.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_982272
• Locus ID: 81704
• UniProt ID: Q8NF50
• Cytogenetics: 9p24.3
• Refseq Size: 7257
• Refseq ORF: 6093
• Synonyms: HEL-205; MRD2; ZIR8
• Summary: This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]