SERPING1 (NM_001032295) Human Recombinant Protein

CAT#: TP323112

Recombinant protein of human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 2


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Size
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC223112. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 52.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001027466
Locus ID 710
UniProt ID P05155, E9KL26
Cytogenetics 11q12.1
Refseq Size 1832
Refseq ORF 1500
Synonyms C1IN; C1INH; C1NH; HAE1; HAE2
Summary 'This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, May 2020]'
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades

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