Hmox1 (NM_010442) Mouse Recombinant Protein

CAT#: TP503944

Purified recombinant protein of Mouse heme oxygenase 1 (Hmox1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from Mouse cDNA ORF Clone, MR203944, encoding Mouse full-length Hmox1.
• Tag: C-MYC/DDK
• Predicted MW: 33.4 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_034572
• Locus ID: 15368
• UniProt ID: P14901, Q3U5U6
• Cytogenetics: 8 C1
• Refseq Size: 1564
• Refseq ORF: 867
• Synonyms: D8Wsu38e; Hemox; Hmox; HO-1; HO1; Hsp32
• Summary: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. [UniProtKB/Swiss-Prot Function]