Aspa (NM_023113) Mouse Recombinant Protein
CAT#: TP504432
Purified recombinant protein of Mouse aspartoacylase (Aspa), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
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Specifications
Product Data | |
Species | Mouse |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
A DNA sequence from Mouse cDNA ORF Clone, MR204432, encoding Mouse full-length Aspa.
|
Tag | C-MYC/DDK |
Predicted MW | 35.3 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_075602 |
Locus ID | 11484 |
UniProt ID | Q8R3P0 |
Cytogenetics | 11 B4 |
Refseq Size | 1537 |
Refseq ORF | 939 |
Synonyms | Acy-2; Acy2; nur7 |
Summary | This gene encodes an enzyme that deacteylates N-acetyl-L-aspartic acid (NAA) in the brain to yield acetate and L-aspartate. In humans, alterations in neuronal NAA concentration are associated with many neurodegenerative diseases (decrease associated with epilepsy, multiple sclerosis, myotrophic lateral sclerosis, and Alzheimer's disease; increase associated with Canavan disease). In mouse, mutations in this gene, which cause accumulation of NAA, result in demyelination and spongy degeneration in the CNS and serve as a pathophysiological model for Canavan disease. [provided by RefSeq, Dec 2012] |
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