Rora (BC003757) Mouse Recombinant Protein

CAT#: TP507347

Purified recombinant protein of Mouse RAR-related orphan receptor alpha (cDNA clone MGC:5892 IMAGE:3592667), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Tag: C-MYC/DDK
• Predicted MW: 87.2 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Reference Data

• Locus ID: 19883
• Cytogenetics: 9 37.45 cM
• Refseq Size: 2381
• Refseq ORF: 1380
• Synonyms: ROR1, ROR2, ROR3, Nr1f1, staggerer
• Summary: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]