Furin (NM_001081454) Mouse Recombinant Protein
CAT#: TP510693
Purified recombinant protein of Mouse furin (paired basic amino acid cleaving enzyme) (Furin), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
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Specifications
Product Data | |
Species | Mouse |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
A DNA sequence from Mouse cDNA ORF Clone, MR210693, encoding Mouse full-length Furin.
|
Tag | C-MYC/DDK |
Predicted MW | 87.2 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001074923 |
Locus ID | 18550 |
UniProt ID | P23188 |
Cytogenetics | 7 45.65 cM |
Refseq Size | 4166 |
Refseq ORF | 2379 |
Synonyms | 9130404I01Rik; Fur; PACE; Pcsk3; SPC1 |
Summary | This gene encodes a calcium-dependent serine endoprotease that proteolytically activates different proprotein substrates traversing the secretory pathway. The encoded protein undergoes proteolytic autoactivation during which an N-terminal propeptide is cleaved to generate the mature protein. Mice lacking the encoded protein die at an embryonic stage and display hemodynamic insufficiency, cardiac ventral closure defect, axial rotation defect and abnormal yolk sac vasculature. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
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