Il12rb1 (NM_008353) Mouse Recombinant Protein
CAT#: TP520916
Purified recombinant protein of Mouse interleukin 12 receptor, beta 1 (Il12rb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
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Specifications
Product Data | |
Species | Mouse |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
A DNA sequence from Mouse cDNA ORF Clone, MR220916, encoding Mouse full-length Il12rb1.
|
Tag | C-MYC/DDK |
Predicted MW | 82.2 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_032379 |
Locus ID | 16161 |
UniProt ID | Q60837 |
Cytogenetics | 8 34.21 cM |
Refseq Size | 2873 |
Refseq ORF | 2214 |
Synonyms | CD212; IL-12R[b] |
Summary | Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. [UniProtKB/Swiss-Prot Function] |
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