Adarb1 (NM_001024837) Mouse Recombinant Protein
CAT#: TP524167
Purified recombinant protein of Mouse adenosine deaminase, RNA-specific, B1 (Adarb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
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Specifications
Product Data | |
Species | Mouse |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
A DNA sequence from Mouse cDNA ORF Clone, MR224167, encoding Mouse full-length Adarb1.
|
Tag | C-MYC/DDK |
Predicted MW | 78.5 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001020008 |
Locus ID | 110532 |
UniProt ID | Q91ZS8 |
Cytogenetics | 10 39.72 cM |
Refseq Size | 6602 |
Refseq ORF | 2133 |
Synonyms | 1700057H01Rik; Adar2; AW124433; AW558573; BB220382; D10Bwg0447e; Red1 |
Summary | This gene encodes a double-stranded-RNA-specific adenosine deaminase that is involved in editing pre-mRNAs by site-specific conversion of adenosine (A) to inosine (I). Substrates for this enzyme include ionotropic glutamate receptors (GluR2-6) and serotonin receptor (5HT2C). Studies in rodents have shown that this protein can modify its own pre-mRNA by A->I editing to create a novel acceptor splice site, alternative splicing to which results in down regulation of its protein expression. Additional splicing events result in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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