Nr0b1 (NM_007430) Mouse Recombinant Protein

CAT#: TP524919

Purified recombinant protein of Mouse nuclear receptor subfamily 0, group B, member 1 (Nr0b1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from Mouse cDNA ORF Clone, MR224919, encoding Mouse full-length Nr0b1.
• Tag: C-MYC/DDK
• Predicted MW: 53 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_031456
• Locus ID: 11614
• UniProt ID: Q61066, Q53ZY9
• Cytogenetics: X 39.67 cM
• Refseq Size: 1794
• Refseq ORF: 1416
• Synonyms: Ahc; Ahch; AHX; DAX-1; Dax1
• Summary: This gene encodes an orphan nuclear receptor protein that plays a key role in differentiation of the gonads. This protein regulates steroidogenic factor 1 (Sf-1) in a dose-dependent manner, sometimes functioning as a repressor of SF-1 target genes, and sometimes functioning as a co-activator. Overexpression of this gene can cause feminization of the XY male gonads. This gene is also involved in the maintenance of embryonic stem cell pluripotancy. Mutations in the related gene in human cause congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, May 2015]