Msh5 (NM_001146215) Mouse Recombinant Protein
CAT#: TP526215
Purified recombinant protein of Mouse mutS homolog 5 (Msh5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
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Specifications
Product Data | |
Species | Mouse |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
A DNA sequence from Mouse cDNA ORF Clone, MR226215, encoding Mouse full-length Msh5.
|
Tag | C-MYC/DDK |
Predicted MW | 92.6 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001139687 |
Locus ID | 17687 |
UniProt ID | Q9QUM7, A0A0R4IZY8 |
Cytogenetics | 17 18.57 cM |
Refseq Size | 2693 |
Refseq ORF | 2502 |
Synonyms | Mut5 |
Summary | This gene encodes a member of the MutS family of proteins that play critical roles in DNA mismatch repair and meiotic homologous recombination processes. Mice lacking the encoded protein are viable but sterile, with severe defects in spermatogenesis in males and complete loss of ovarian structures in females. Mutations in a similar gene in humans have been shown to cause common variable immune deficiency (CVID) and immunoglobulin A deficiency. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
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