Itgb4 (NM_133663) Mouse Recombinant Protein
CAT#: TP527156
Purified recombinant protein of Mouse integrin beta 4 (Itgb4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
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Specifications
Product Data | |
Species | Mouse |
Expression Host | HEK293T |
Tag | C-MYC/DDK |
Predicted MW | 195.1 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Reference Data | |
RefSeq | NP_598424 |
Locus ID | 192897 |
Cytogenetics | 11 80.91 cM |
Refseq Size | 6010 |
Refseq ORF | 5256 |
Synonyms | AA407042; C230078O20; CD104 |
Summary | Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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