PKC epsilon (PRKCE) (NM_005400) Human Recombinant Protein
CAT#: TP710186
Purified recombinant protein of Human protein kinase C, epsilon (PRKCE), full length, with C-terminal DDK tag, expressed in sf9, 20ug
Specifications
Product Data | |
Species | Human |
Expression Host | Sf9 |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC217702, encoding human full-length PRKCE
|
Tag | C-DDK |
Predicted MW | 83.5 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_005391 |
Locus ID | 5581 |
UniProt ID | Q02156, L7RTI5 |
Cytogenetics | 2p21 |
Refseq Size | 5537 |
Refseq ORF | 2211 |
Synonyms | nPKC-epsilon; PKCE |
Summary | 'Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]' |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401658 | PRKCE HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LY401658 | Transient overexpression lysate of protein kinase C, epsilon (PRKCE) |
USD 605.00 |
|
PH317702 | PRKCE MS Standard C13 and N15-labeled recombinant protein (NP_005391) |
USD 2,055.00 |
|
TP317702 | Recombinant protein of human protein kinase C, epsilon (PRKCE) |
USD 788.00 |
|
TP720143 | Recombinant protein of human protein kinase C, epsilon (PRKCE) |
USD 330.00 |
{0} Product Review(s)
Be the first one to submit a review