GSK3 beta (GSK3B) (NM_002093) Human Recombinant Protein
CAT#: TP710339
Purified recombinant protein of Human glycogen synthase kinase 3 beta (GSK3B), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9, 20ug
Specifications
Product Data | |
Species | Human |
Expression Host | Sf9 |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC200468, encoding human full-length GSK3B
|
Tag | C-DDK |
Predicted MW | 47.9 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_002084 |
Locus ID | 2932 |
UniProt ID | P49841 |
Cytogenetics | 3q13.33 |
Refseq Size | 1639 |
Refseq ORF | 1299 |
Synonyms | glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; GSK3beta isoform |
Summary | 'The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]' |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Alzheimer's disease, Axon guidance, Basal cell carcinoma, B cell receptor signaling pathway, Cell cycle, Chemokine signaling pathway, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Hedgehog signaling pathway, Insulin signaling pathway, Melanogenesis, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, T cell receptor signaling pathway, Wnt signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC419542 | GSK3B HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC431916 | GSK3B HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY419542 | Transient overexpression lysate of glycogen synthase kinase 3 beta (GSK3B), transcript variant 1 |
USD 396.00 |
|
LY431916 | Transient overexpression lysate of glycogen synthase kinase 3 beta (GSK3B), transcript variant 2 |
USD 396.00 |
|
PH300468 | GSK3B MS Standard C13 and N15-labeled recombinant protein (NP_002084) |
USD 2,055.00 |
|
TP300468 | Recombinant protein of human glycogen synthase kinase 3 beta (GSK3B) |
USD 823.00 |
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