Il1b (NM_008361) Mouse Recombinant Protein

CAT#: TP720033XL

Recombinant protein of mouse Interleukin-1B/IL-1B

Specifications

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Val118-Ser269
• Tag: tag free
• Predicted MW: 17.4 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Lyophilized from a 0.2 um filtered solution of 50mM Tris-HCl, 50mM NaCl, pH 8.0.
• Bioactivity: ED50 is less than 0.01 ng/ml as determined by the dose-dependent stimulation of mouse D10S cells. Specific Activity of 1.0 x 108 IU/mg.
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_032387
• Locus ID: 16176
• UniProt ID: P10749
• Cytogenetics: 2 62.97 cM
• Refseq Size: 1328
• Refseq ORF: 807
• Synonyms: IL-; Il-1b; IL-1beta
• Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1. The encoded protein plays a role in thymocyte proliferation and is involved in the inflammatory response. [provided by RefSeq, Aug 2015]