Grancalcin (GCA) (NM_012198) Human Recombinant Protein

CAT#: TP720123XL

Recombinant protein of human grancalcin, EF-hand calcium binding protein (GCA)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Ile217
• Tag: N-GST
• Predicted MW: 50.2 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 500mM Nacl, pH 8.5 .
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Store at -80°C.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_036330
• Locus ID: 25801
• UniProt ID: P28676
• Cytogenetics: 2q24.2
• Synonyms: GCL
• Summary: This gene encodes a calcium-binding protein that is abundant in neutrophils and macrophages. In the absence of divalent cation, this protein localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions. Alternative splicing and use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Aug 2016]