LI Cadherin (CDH17) (NM_004063) Human Recombinant Protein
CAT#: TP720740L
Purified recombinant protein of Human cadherin 17, LI cadherin (liver-intestine) (CDH17), transcript variant 1
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Gln23-Met787
|
Tag | C-His |
Predicted MW | 86 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.4. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_004054 |
Locus ID | 1015 |
UniProt ID | Q12864 |
Cytogenetics | 8q22.1 |
Refseq Size | 3697 |
Refseq ORF | 2496 |
Synonyms | CDH16; HPT-1; HPT1 |
Summary | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
Protein Families | Transmembrane |
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