OB Cadherin (CDH11) (NM_001797) Human Recombinant Protein

CAT#: TP720754L

Purified recombinant protein of Human cadherin 11, type 2, OB-cadherin (osteoblast) (CDH11)

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Phe23-Thr617
• Tag: C-6His
• Predicted MW: 66.63 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001788
• Locus ID: 1009
• UniProt ID: P55287
• Cytogenetics: 16q21
• Refseq Size: 3654
• Refseq ORF: 2388
• Synonyms: CAD11; CDHOB; ESWS; OB; OSF-4
• Summary: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Transmembrane