XPNPEP3 (NM_022098) Human Recombinant Protein

CAT#: TP720858L

Purified recombinant protein of Human X-prolyl aminopeptidase (aminopeptidase P) 3, putative (XPNPEP3), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Ser507
• Tag: N-His&C-His
• Predicted MW: 60.2 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 μm filtered solution of 25mM Tris, 1mM DTT, pH 7.3.
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_071381
• Locus ID: 63929
• UniProt ID: Q9NQH7
• Cytogenetics: 22q13.2
• Refseq Size: 8027
• Refseq ORF: 1521
• Synonyms: APP3; ICP55; NPHPL1
• Summary: The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.[provided by RefSeq, Mar 2011]
• Protein Families: Druggable Genome, Protease