BNIP3 (NM_004052) Human Recombinant Protein
CAT#: TP720934XL
Purified recombinant protein of Human BCL2/adenovirus E1B 19kDa interacting protein 3 (BNIP3), nuclear gene encoding mitochondrial protein
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Leu166
|
Tag | N-His |
Predicted MW | 20.6 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_004043 |
Locus ID | 664 |
UniProt ID | Q12983, Q6NVY4 |
Cytogenetics | 10q26.3 |
Refseq Size | 1535 |
Refseq ORF | 582 |
Synonyms | NIP3 |
Summary | This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014] |
Protein Families | Druggable Genome, Transmembrane |
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