UBC3B (UBE2R2) (NM_017811) Human Recombinant Protein
CAT#: TP720963M
Purified recombinant protein of Human ubiquitin-conjugating enzyme E2R 2 (UBE2R2)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Ser238
|
Tag | N-His |
Predicted MW | 29.3 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, pH 7.5. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_060281 |
Locus ID | 54926 |
UniProt ID | Q712K3 |
Cytogenetics | 9p13.3 |
Refseq Size | 4457 |
Refseq ORF | 714 |
Synonyms | CDC34B; E2-CDC34B; UBC3B |
Summary | Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008] |
Protein Pathways | Ubiquitin mediated proteolysis |
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