UBC3B (UBE2R2) (NM_017811) Human Recombinant Protein

CAT#: TP720963M

Purified recombinant protein of Human ubiquitin-conjugating enzyme E2R 2 (UBE2R2)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Ser238
• Tag: N-His
• Predicted MW: 29.3 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, pH 7.5.
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_060281
• Locus ID: 54926
• UniProt ID: Q712K3
• Cytogenetics: 9p13.3
• Refseq Size: 4457
• Refseq ORF: 714
• Synonyms: CDC34B; E2-CDC34B; UBC3B
• Summary: Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
• Protein Pathways: Ubiquitin mediated proteolysis