UBE2M (NM_003969) Human Recombinant Protein

CAT#: TP720986M

Purified recombinant protein of Human ubiquitin-conjugating enzyme E2M (UBE2M)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Lys183
• Tag: tag free
• Predicted MW: 20.9 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 um filtered solution of 50mM HEPES, pH 7.5, 2mM DTT, 150mM NaCl, 10% Glycerol.
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_003960
• Locus ID: 9040
• UniProt ID: P61081, A0A024R4T4
• Cytogenetics: 19q13.43
• Refseq Size: 1536
• Refseq ORF: 549
• Synonyms: hUbc12; UBC-RS2; UBC12
• Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq, Jul 2008]
• Protein Pathways: Ubiquitin mediated proteolysis