Ornithine Decarboxylase (ODC1) (NM_002539) Human Recombinant Protein
CAT#: TP721016XL
Purified recombinant protein of Human ornithine decarboxylase 1 (ODC1)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Val461
|
Tag | N-T7&C-His |
Predicted MW | 53.5 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002530 |
Locus ID | 4953 |
UniProt ID | P11926 |
Cytogenetics | 2p25.1 |
Refseq Size | 2307 |
Refseq ORF | 1383 |
Synonyms | BABS; NEDBA; NEDBIA; ODC |
Summary | This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013] |
Protein Families | Druggable Genome |
Protein Pathways | Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
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