RSPO3 (NM_032784) Human Recombinant Protein
CAT#: TP721065M
Purified recombinant protein of Human R-spondin 3 homolog (Xenopus laevis) (RSPO3)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Gln22-His272
|
Tag | C-Fc&His |
Predicted MW | 56.3 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_116173 |
Locus ID | 84870 |
UniProt ID | Q9BXY4 |
Cytogenetics | 6q22.33 |
Refseq Size | 4583 |
Refseq ORF | 816 |
Synonyms | CRISTIN1; PWTSR; THSD2 |
Summary | This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013] |
Protein Families | Druggable Genome, Secreted Protein |
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